Cyclobenzaprine

However, because drugs affect each person differently, we cannot guarantee that this information includes all possible side effects. This information is not a substitute for medical advice. Always discuss possible side effects with a healthcare professional who knows your medical history.

However, your physician can better decide which drug is better for your back pain. Cyclobenzaprine is a centrally acting skeletal muscle relaxant structurally related to tricyclic antidepr[7]essants. Cyclobenzaprine relieves skeletal muscle flexeril muscle relaxers spasms of local origin without interfering with muscle function. In preclinical research, cyclobenzaprine reduced skeletal muscle hyperactivity. Research indicates that it primarily acts within the central nervous system in the brain stem.

• The extended-release formulation should be administered at the same time each day.
• This timeline is appropriate for an immediate-release formulation.
• If an antidepressant helps to some degree but you still have pain, talk to a healthcare provider about incorporating a medication from another drug class into your treatment plan.

This enables the provider to evaluate for any potential interactions and helps them keep the patient safe. Even if it feels like the effects of cyclobenzaprine have worn off, the drug may not be completely eliminated from the body yet and could cause serious interactions with other substances. Muscle relaxers (also called muscle relaxants) are prescription medications that affect muscle function. Healthcare providers prescribe them to treat several symptoms, such as muscle spasms, spasticity and musculoskeletal pain. Drug interactions may change how your medications work or increase your risk for serious side effects.

Flexeril is a strong muscle relaxant used with rest and physical therapy to treat muscle spasms. However, it is only for short-term relief from acute muscle pain and other skeletal conditions. It works by directly reducing muscle hyperactivity and decreasing the transmission of pain. Cyclobenzaprine can increase the effects of CNS depressants, such as alcohol, opioids, allergy medications, and sleeping pills.

If you experience any of the following symptoms, call your doctor immediately:

This means you may need to take it with other medications. This medicine may cause some people to have blurred vision or to become drowsy, dizzy, or less alert than they are normally. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or are not alert and able to see well. If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. If you cannot swallow the capsule whole, you may open the capsule and sprinkle the contents over one tablespoon of applesauce.

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After you eat the mixture, take a drink, and swish and swallow to make sure that you have received all the medication.

Cyclobenzaprine side effects

Cyclobenzaprine has moderate interactions with at least 43 different drugs. Secondary endpoints included a physician’s evaluation of the presence and extent of palpable muscle spasm. In light of these findings, therapy with FLEXERIL in the elderly should be initiated with a 5 mg dose and titrated slowly upward. It is not known whether this drug is excreted in human milk.

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It is also sometimes prescribed off-label to treat fibromyalgia pain. Do not use cyclobenzaprine if you have taken an MAO inhibitor in the past 14 days. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine. Ask your healthcare professional how you should dispose of any medicine you do not use. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur.

In three of these studies there was a significantly greater improvement with FLEXERIL than with diazepam, while in the other studies the improvement following both treatments was comparable. Cyclobenzaprine caused slight to moderate increase in heart rate in animals. Flexeril is the brand name for Cyclobenzaprine, a prescription muscle relaxer that is similar to a class of Antidepressant drugs called Tricyclic Antidepressants.

Cyclobenzaprine is a centrally acting skeletal muscle relaxant structurally related to tricyclic antidepressants. Cyclobenzaprine is a tricyclic amine salt that works in the central nervous system (CNS) as a depressant that reduces muscle hyperactivity. Clinical indications for cyclobenzaprine are described below. Concomitant use of monoamine oxidase (MAO) inhibitors or within 14 days after their discontinuation. Hyperpyretic crisis seizures, and deaths have occurred in patients receiving cyclobenzaprine (or structurally similar tricyclic antidepressants) concomitantly with MAO inhibitor drugs. The plasma concentration of cyclobenzaprine is increased in the elderly (see CLINICAL PHARMACOLOGY, Pharmacokinetics, Elderly).